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Changing Use of Fetal Bovine Serum (FBS) in Labs




A brand new paper coauthored by PETA Science Consortium Worldwide e.V. exhibits find out how to enhance analysis by changing media containing fetal bovine serum (FBS) with animal-free media.

Yearly, an estimated 1.8 million unborn calves are killed worldwide to provide FBS—a mix of molecules, together with hormones, proteins, and development components, obtained from the blood of fetal calves after their moms are slaughtered for meals. FBS, which is utilized in laboratories to assist develop cells in petri dishes (in vitro), contributes to the reproducibility drawback in analysis, as variations between batches of FBS enhance the variability of research utilizing cells grown in it.

The paper, revealed in Toxicology in Vitro, describes the transition of a human lung cell line generally utilized in analysis to cell tradition media with out FBS or another animal-derived parts. The success of this challenge units a precedent for making the identical transition for different cell varieties and has far-reaching implications for the sector of in vitro analysis.

Scientific organizations, such because the Organisation for Financial Co-operation and Growth and the European Union Reference Laboratory for Alternate options to Animal Testing, have inspired the transition from utilizing FBS to utilizing animal-free, chemically outlined media.

PETA scientists are actually sharing the publication with laboratories. They’re additionally working to transition different cells out of FBS and inspiring researchers to take action as nicely.


The Science Consortium and its members have donated hundreds of thousands of {dollars} towards bettering and implementing non-animal check strategies, together with funding their growth and validation in addition to organizing free workshops, webinars, and coaching alternatives for scientists.



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